Nick Hendricks (Jason Bateman), Dale Arbus (Charlie Day), and Kurt Buckman (Jason Sudeikis) are friends who despise their bosses. Nick works at a financial firm for Dave Harken (Kevin Spacey), who abuses Nick constantly. Nick has put up with it in hopes of a promotion, but Harken instead gives Nick's desired job to himself, angering Nick. Dale is a dental assistant to Dr. Julia Harris (Jennifer Aniston), who constantly wants to have sex with her knocked out patients as well as Dale, who has a fiancee, Stacy (Lindsay Sloane), but is also a registered sex offender by accident. Julia even forces him to look at her while she wears only a lab coat and panties. Kurt enjoys his job working at an industrial company for Jack Pellitt (Donald Sutherland), who treats Kurt like a son, but Jack dies of a heart attack one day, leaving his biological, cocaine-addicted son Bobby (Colin Farrell) in charge. Bobby threatens to run the company into the ground by having the overweight and handicapped employees fired along with doing cocaine and having prostitutes in his office.
